Very low dose at-home treatment
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Only $129/month
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“I was so tired of feeling numb and tired all of the time on my antidepressants before joining Joyous, and now I feel like myself again.”

P.J.

I didn’t even know how much anxiety I was carrying until it wasn’t there anymore.

R.L.

This is awesome. My brain feels like it's fully functioning but just giving me a break from like 70% of my thoughts.

A.W.

Joyous is a remarkable, life altering, life saving therapy. I'd recommend to all my friends struggling with complicated grief, anxiety, depression, or PTSD

J.A.

Bring JOY back to your life.

Change your mind with ketamine microdose therapy
$129 / month
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Patients share

What is Ketamine?

Ketamine is a dissociative anesthetic that was FDA-approved in 1970, best known for its use as an anesthetic in medical procedures. What sets it apart from other anesthetics is its ability to provide effective pain relief without impairing the respiratory system.

In recent decades, ketamine has been discovered to be a breakthrough for mental health, with significant clinical data showing patients with depression, anxiety, and PTSD, even those with treatment-resistant conditions, finding relief from symptoms.

The Joyous treatment plan, which uses psycholytic doses (very low doses) of ketamine, paired with curated treatment courses and therapy practices that has shown to:
  • Produce an immediate sense of calm
  • Boost self-compassion
  • Reduce impulsive reactions and judgement
  • Build new neural pathways & break negative thought patterns
  • Enhance receptivity to therapy and self-care practices
Is ketamine safe?
Is ketamine safe?

Ketamine's safety profile is well-established in clinical settings like ours, making it a vital tool in medical practice. Its unique characteristic of not impairing the respiratory system contributes to its broad application and acceptability.

Administered by our trained medical professionals in controlled doses, it's considered a safe anesthetic option for a wide range of patients. In fact, its safety is such that it's even used in surgeries with children. By adhering to stringent guidelines and protocols, we ensure that potential risks are minimized, reinforcing ketamine's position as a dependable choice within our healthcare environment.

What does it feel like?
What does it feel like?

After about 15 minutes of taking your dose you may begin to feel a subtle calming and possible lightheadedness.

Most people report having a positive experience with little-to-no side effects. However, you may feel a little tipsy and a bit “out of it” for 30-40 minutes.

Many patients find the immediate effects to be very pleasant and a great time to reflect on their own thoughts, but if it doesn’t feel good for you then lowering the dose, or splitting your dose throughout the day, seems to reduce these side effects. You will begin to learn how ketamine affects you almost immediately.

Over the first few weeks, we will track and adjust your dose based on how you feel. While you are learning, you may experience some side effects, for example lightheadedness or even nausea. All of these feelings are normal, and can be reduced through simple adjustments to the protocol.

Can I keep taking other medications?
Can I keep taking other medications?

Many medications are compatible with low-dose ketamine, including SSRIs and benzodiazepines. The list of contraindicated medications is short, but your Joyous medical provider will review your current medications and help you decide if our medication is a good fit for you.

Many of our patients continue to take their antidepressant and anxiety medications throughout treatment without any issues. Be sure to bring your current list of medications to your consultation to review with your provider.

How quickly will the medication work?
How quickly will the medication work?

Our patients have reported experiencing an immediate sense of calm, with consistent and gradual improvements over time. Low-dose ketamine treatment can also produce a heightened receptivity to therapy, allowing patients to practice therapy or self-care exercises to optimize treatment during the session.

Over 89% of Joyous patients report improvements in depression and anxiety symptoms in the first month of treatment. However, all bodies are different, and some patients experience improvements in month 2 or 3 of treatment once they find the right dosage and start to see the impact of the treatment courses on their daily lives.

The Joyous Treatment Plan

Personalized treatment & individualized care

Joyous treatment is completely personalized to each patient. Once you receive your medication, we'll text you daily check-ins to monitor your progress and understand how you're responding to treatment. This will help us adjust your dosage specifically for you.

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Enhance neuroplasticity & build a new mindset

Joyous treatment combines very low-dose ketamine medication with curated psychology-based treatment courses and content to help your brain build new neural connections and make gradual, consistent mental health improvements, far beyond treatment.

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Deeper than surface-level relief

The Joyous program is designed for patients to "graduate" from treatment. The medication and treatment courses are meant to enhance patient receptivity to therapy, process underlying emotions, heal old thought patterns, and build valuable skills to handle life's ups and downs.

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How long do I need to take this treatment?
How long do I need to take this treatment?

There is no set timeline, you can participate in our low-dose ketamine treatment long term if you feel it is benefitting you, or you can come off it at any time.

Many of our patients have been on the Joyous treatment for years and still have mental health benefits, while others stop when they feel that is right for them. There have been no reported complications or problems with taking our ketamine treatment for extended periods of time when taken as prescribed.

When/if you decide to come off of the medication, withdrawal symptoms are rare in a clinical setting, and we will provide you with our medical recommendations to ensure that you can stop treatment safely. The length of treatment is personal to every patient, and you have complete say over how long you take ketamine.

What happens if I stop the treatment?
What happens if I stop the treatment?

When you're ready to stop treatment, our team will create a plan to help you stop treatment safely. Withdrawal symptoms are rare in our clinical setting. As time passes and the ketamine is out of your system, the neuroplasticity benefits may begin to dull, but can be reactivated by starting treatment again.

Who is a good candidate for Joyous?
Who is a good candidate for Joyous?

Good candidates for the Joyous treatment are people who have tried therapy and/or traditional medications in the past and didn't feel like that was enough or the right kind of treatment for them. People who suffer from depression and anxiety commonly experience relief from our treatment even when other treatments failed.

Treatment Pricing

$129
/ month
Cancel anytime. FSA/HSA accepted.
Get started in 4 easy steps:
1
Self assessment
2
Meet a medical provider online
3
Pay for the first month
4
Get your medication delivered
Get Started
What if I want to cancel?
What if I want to cancel?

Joyous treatment has no monthly commitment and can be canceled anytime as long as you cancel before your refill has been sent out. Please contact the Care Team via text or email to request cancelation; you will be prompted to answer a few simple questions about why you are leaving so we can understand your unique situation and can improve our service. Once the form has been submitted, we will review and We will also provide you with some recommendations on what to do post-treatment to ensure you remain happy and healthy.

Does insurance cover this?
Does insurance cover this?

Currently, insurance companies do not cover our ketamine treatments or consultations. We do accept HSA and FSA funds if you utilize those accounts in your health care. Some insurance plans cover different forms of ketamine treatment, however these options are normally difficult to find and expensive. At Joyous, we do everything we can to keep our service and treatment plan as affordable as possible, because we believe that mental health care is a priority and not a privilege.

Program includes
Monthly supply of medication shipped to you
Personalized dosage and treatment plan
Daily and weekly monitoring to track progress
Check-in appointments with a provider
Guides, resources, and courses in our Be Joyous patient portal

What are you hoping to achieve?

Mark all that apply
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What Do Our Patients Experience?

What to expect

Your Joyous medical provider will send a prescription to the pharmacy after your free consultation, and we will ship your medication in 2-3 business days. Prepare to make the most of your treatment by starting the treatment courses in the Be Joyous patient portal!

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How it feels

The medication is a microdose, a very low dose that may produce an immediate sense of calm or "tipsiness". It should not be overwhelming or intense, but provides a moment to be reflective, breathe, and do something enjoyable like dance or listen to music.

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Finding the right dose

You will receive daily texts to monitor how you're feeling and dosage recommendations until you find the dose that feels right for you. You can text or email our Care Team and providers if you have any questions or need assistance.

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How does it compare to other Ketamine products?
How does it compare to other Ketamine products?

Other ketamine treatments can range between $500-$3000/month for high doses of ketamine. Higher doses create more of a "psychedelic" experience which can be overwhelming for some patients and benefit from integration coaching after the experience. Joyous uses microdoses, small doses where our patients remain fully coherent and oriented, able to engage with therapy and therapeutic exercises from the comfort of their home. All for just $129/month, no monthly commitment, making us the most affordable at-home ketamine treatment option.

Comparing Joyous to other in-home ketamine treatments
How do I take the ketamine microdose?
How do I take the ketamine microdose?

Our ketamine medication comes in the form of "troches," small waxy squares that you place between your cheek and lip for about 15 minutes. Let the troche melt and once finished, you can spit the remaining wax out. Do not eat or drink while the troche is in to optimize absorption.

Is there downtime?
Is there downtime?

Joyous uses a proprietary low dose ketamine protocol that is highly effective without the psychedelic experience. Our treatment uses a psycholytic dose that allows you to move beyond the superficial layers of your day-to-day mind, can help heal unhealthy neural pathways, and help you achieve the clarity you need to live the life you deserve. Our treatment requires no down time, special conditions, or "trip sitters," because our doses are low enough to not cause a psychedelic experience, and our providers monitor patient side effects and progress virtually. You can safely take our medication from the comfort of your home and continue to live your life.

How is it different from IV ketamine?
How is it different from IV ketamine?

Our low dose ketamine protocol can be taken orally from the comfort of your home and does not require you to stop or pause your daily tasks. Low dose ketamine is considered a psycholytic dose, not a psychedelic dose. This means that our patients experience the positive benefits of improved mood, new perspective, and improved neural connectivity without the psychedelic experience.

Is it compatible with other antidepressants?
Is it compatible with other antidepressants?

Low-dose ketamine medication is compatible with other antidepressants. Many of our patients continue to take their antidepressants while on our treatment and have not had any issues. Your Joyous medical provider will review your medical history and current list of medications to ensure that Joyous is a good fit for you and there aren't any interactions.

You’re not alone

Meet the Be-Joyous community

Be Joyous™ is an empowering community portal for Joyous patients, offering a space to connect, share, and grow together. It’s a safe, judgment-free zone for emotional expression and support.

On Be Joyous you'll:
  • Get access to a wealth of resources curated to improve your mental health
  • Engage in meaningful conversations with a supportive community
  • Find support, connection, and inspiration
  • Gain new perspectives and coping strategies
  • Find guided meditations, exercises, and feel-good content to help you build a more joyful mindset
Become a patient

Answers to any question

Ask anything...
Is Ketamine FDA Approved?
Is Ketamine FDA Approved?

Ketamine was FDA approved in 1970 as a dissociative analgesic and has since been used in clinics and hospitals globally. In recent decades, ketamine has been used off-label, to help treat mental health conditions including treatment-resistant depression and anxiety. Joyous uses compounded very low-dose ketamine lozenges as part of the treatment program, which are prescribed off-label.

How do I cancel my subscription?
How do I cancel my subscription?

You can cancel your prescription at any time by reaching out to our Care Team via text (844-774-0909) or email (care@joyous.team). They will send a short survey to help us improve our service and provide recommendations for stopping treatment. Once submitted, they will cancel your subscription. If you ever want to restart treatment in the future, we're always here to help!

How is Ketamine different than SSRIs?
How is Ketamine different than SSRIs?

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How long do you have to be on it?
How long do you have to be on it?

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From the Joyous blog

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Daily Microdose & Progress Check-ins

Rapid Relief & Immediate Sense of Calm

Affordable! Only $129/month

Compatible with Other Medications

Safe, Effective, and Well-tolerated

Very Low Dose Treatment

Available in Most States

Experience Quick Relief and Lasting Improvement Through Our Proprietary Protocol & Personalized Guidance

Our treatment plan includes:
Telehealth Consultation
Daily texts & check-in Surveys
Digital intake assessment
Patient Portal- Coming soon!
Prompt medication delivery

Transforming Minds, Restoring Lives

Our proprietary very low dose at-home protocol can produce relief from depression and anxiety symptoms and lead to gradual and consistent mental health improvements. Learn how our daily guidance and personalized recommendations can optimize your treatment plan.

Is Joyous right for me?

Start by taking a survey to ensure that our treatment is a good match for you. If you qualify, you’ll schedule an online video appointment to get approved for the treatment. Then we’ll ship the medication directly to your door within 2-3 days.

Is This Medication Safe?

The medication we use was first approved by the FDA for use as an anesthetic in the 1970s, and is widely viewed as safe, effective, and well-tolerated for most people (with the exception of individuals with uncontrolled high blood pressure, history of psychosis, or heart rhythm problems). to ensure that our treatment is a good match for you. If you qualify, you’ll schedule an online video appointment to get approved for the treatment. Then we’ll ship the medication directly to your door within 3-5 days.

How will I feel when I start treatment?

After ~15 minutes of taking your dose, you might initially experience a subtle calming sensation and potential lightheadedness, with most individuals reporting a generally positive experience and minimal side effects. You'll quickly learn how the medication affects you, and over the first few weeks, we'll monitor and adapt your dosage based on your comfort.

Can I take other medications?

Many medications are compatible with this medication, including traditional antidepressants and anxiety medications. Be sure to share your medical history and current list of medications with your Joyous provider in your initial consultation to ensure that Joyous is a safe and effective treatment option for you. They will confirm that there are no medication interactions and provide guidance around how to take the medication. Our patients who continue to take their antidepressant and anxiety medications during this treatment have not experienced problems.

How quickly will the medication work?

The medication we use in our treatment protocol can produce immediate calming effects, and can spark the beginning of gradual and consistent mental health improvement. Our treatment can produce a heightened receptivity to therapy, allowing patients to practice therapy or self-care exercises to optimize treatment during the session. This helps our patients experience deeper than surface-level symptom relief.

How do I take the medication?

Our medication comes in the form of a lozenge, which looks like a little waxy cube and dissolves in your mouth. You will take your dosage out of the package, and then place it in your mouth between your upper jaw and cheek. If your ideal dose is ¼ or ½ a lozenge then you can cut it, bite it, or break it. The lozenge will take between 10-15 minutes to dissolve.

Still have questions?

Schedule a consultation with one of our providers to discuss with absolutely zero commitment. We are here to help you feel better!

Feel Better Today!

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“I was so tired of feeling numb and tired all of the time on my antidepressants before joining Joyous, and now I feel like myself again.”

P.J.

I didn’t even know how much anxiety I was carrying until it wasn’t there anymore.

R.L.

This is awesome. My brain feels like it's fully functioning but just giving me a break from like 70% of my thoughts.

A.W.

Joyous is a remarkable, life altering, life saving therapy. I'd recommend to all my friends struggling with complicated grief, anxiety, depression, or PTSD

J.A.

backed by a team of experts

Joyous is born out of a collaboration among medical experts, psychology specialists, and Silicon Valley technologists that are dedicated to helping you become Joyous.

Yossi Fishler

Co-Founder & CEO

Dr. Bobbi K. Leben

Co-Founder & Chief Medical Officier

Eyal Fishler

Co-Founder & CTO

Sharon Niv, Ph.D.

Co-Founder & CXO

Michaela White

Head of Customer Care
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